Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)
Identifying the direct targets of genome-targeting molecules remains a major challenge. To understand how DNA-binding molecules engage the genome, we developed a method that relies on crosslinking of small molecules to isolate chromatin (COSMIC).
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| Format: | Electronic Video |
| Language: | English |
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Cambridge, MA
MyJoVE Corp
2016
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| Series: | Biology
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| Subjects: | |
| Online Access: | CONNECT |
