Neurochemistry of sleep and wakefulness /

Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of mol...

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Bibliographic Details
Other Authors: Monti, Jaime M., Pandi-Perumal, S. R., Sinton, Christopher W.
Format: Electronic eBook
Language:English
Published: Cambridge ; New York : Cambridge University Press, 2008.
Subjects:
Online Access:CONNECT

MARC

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245 0 0 |a Neurochemistry of sleep and wakefulness /  |c edited by Jaime Monti, S.R. Pandi-Perumal, Christopher Michael Sinton. 
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520 |a Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology. 
505 0 |a Cover; Half-title; Title; Copyright; Dedication; Contents; Contributors; Preface; Acknowledgements; Abbreviations; PART I THE NEUROCHEMISTRY OF THE STATES OF SLEEP AND WAKEFULNESS; 1 Neurochemistry of the preoptic hypothalamic hypnogenic mechanism; 2 Neuroanatomical and neurochemical basis of wakefulness and REM sleep systems; 3 Rapid eye movement sleep regulation by modulation of the noradrenergic system; PART II THE INFLUENCE OF NEUROTRANSMITTERS ON SLEEP AND WAKEFULNESS; 4 Gamma-aminobutyric acid and the regulation of paradoxical, or rapid eye movement, sleep 
505 8 |a 5 Acetylcholine modulates sleep and wakefulness: a synaptic perspective6 Histamine in the control of sleep-wakefulness; 7 Dopamine in behavioral state control; 8 Glutamate neurotransmission and sleep; 9 Serotonin and sleep-wake regulation; PART III CHANGING PERSPECTIVES; 10 Melatonin and its receptors: biological function in circadian sleep-wake regulation; 11 Sleep regulatory factors; 12 Adenosine and sleep-wake regulation; 13 Prostaglandins and the regulation of sleep and wakefulness; 14 Neuropeptides and sleep-wake regulation 
505 8 |a 15 Orexins in sleep and wakefulness: rodent models of narcolepsy-cataplexy16 The relevance of experimental pharmacology to currently available sleep-wake therapeutics; Index 
546 |a English. 
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700 1 |a Sinton, Christopher W. 
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