Chimpanzees in biomedical and behavioral research : assessing the necessity /
"For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as rese...
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| Format: | eBook |
| Language: | English |
| Published: |
Washington, D.C. :
National Academies Press,
2011.
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| Subjects: | |
| Online Access: | CONNECT CONNECT |
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| 245 | 0 | 0 | |a Chimpanzees in biomedical and behavioral research : |b assessing the necessity / |c Committee on the Use of Chimpanzees in Biomedical and Behavioral Research, Board on Health Sciences Policy, Institute of Medicine, Board on Life Sciences, Division on Earth and Life Studies ; Bruce M. Altevogt [and others], editors ; Institute of Medicine and National Research Council of the National Academies. |
| 260 | |a Washington, D.C. : |b National Academies Press, |c 2011. | ||
| 300 | |a 1 online resource (x, 190 pages) : |b color illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 380 | |a Bibliography | ||
| 520 | |a "For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future"--Publisher description. | ||
| 505 | 0 | 0 | |t SUMMARY -- |t STUDY BACKGROUND AND CONTEXT -- |t Origin of Study and Committee Statement of Task -- |t Ethical Considerations -- |t METHODS AND ORGANIZATION OF THE REPORT -- |t INTERNATIONAL POLICIES GUIDING CHIMPANZEE USE -- |t SUMMARY OF CHIMPANZEE RESEARCH -- |t Analysis of Federally Supported Research -- |t Analysis of Private-Sector Supported Research -- |t Criteria That Guide the Current Use of Chimpanzees -- |t PRINCIPLES GUIDING THE USE OF CHIMPANZEES IN RESEARCH -- |t Ethologically Appropriate Physical and Social Environments -- |t Criteria to Assess the Necessity of the Chimpanzee for Biomedical -- |t Research -- |t Criteria for Use of the Chimpanzee in Comparative Genomics and -- |t Behavioral Research -- |t REVIEWING THE NECESSITY OF CURRENT CHIMPANZEE -- |t RESEARCH -- |t Monoclonal Antibodies -- |t Development of Chimpanzee Monoclonal Antibodies -- |t Safety Testing of Monoclonal Antibody Therapies -- |t Respiratory Syncytial Virus -- |t HCV Antiviral Drugs -- |t Therapeutic HCV Vaccine -- |t Prophylactic HCV Vaccine -- |t Comparative Genomics -- |t Altruism -- |t Cognition -- |t FUTURE USE OF CHIMPANZEES IN BIOMEDICAL AND -- |t BEHAVIORAL RESEARCH 64 -- |t CONCLUSIONS AND RECOMMENDATIONS 66 -- |g APPENDIXES -- |t A References -- |g B |t Commissioned Paper: Comparison of Immunity to Pathogens in Humans, Chimpanzees, and Macaques -- |g C |t Information-Gathering Agendas -- |g D |t Committee Biographies. |
| 504 | |a Includes bibliographical references. | ||
| 588 | 0 | |a Online resource; title from resource t.p. (National Academies Press, viewed Dec. 27, 2011). | |
| 590 | |a EBSCO eBook Academic Comprehensive Collection North America | ||
| 650 | 0 | |a Chimpanzees as laboratory animals. | |
| 650 | 0 | |a Chimpanzees as laboratory animals |x Moral and ethical aspects. | |
| 700 | 1 | |a Altevogt, Bruce M. | |
| 710 | 2 | |a Committee on the Use of Chimpanzees in Biomedical and Behavioral Research (U.S.) | |
| 730 | 0 | |a WORLDSHARE SUB RECORDS | |
| 776 | 0 | 8 | |i Print version: |t Chimpanzees in biomedical and behavioral research. |d Washington, DC : National Academies Press, ©2011 |z 9780309220392 |w (DLC) 2012359354 |w (OCoLC)783729103 |
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