Fed-batch cultures : principles and applications of semi-batch bioreactors /
Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background...
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Main Authors: | , |
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Format: | eBook |
Language: | English |
Published: |
Cambridge :
Cambridge University Press,
2013.
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Series: | Cambridge series in chemical engineering.
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Subjects: | |
Online Access: | CONNECT CONNECT |
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245 | 1 | 0 | |a Fed-batch cultures : |b principles and applications of semi-batch bioreactors / |c Henry C. Lim, University of California, Irvine, Hwa Sung Shin, Inha University. |
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505 | 0 | |a Introduction to fed-batch bioreactors -- Idealised reactors and fed-batch reactors -- Maximisation of reaction rates and fed-batch operation -- Phenomena that favour fed-batch operations -- Classification and characteristics of fed-batch cultures -- Models based on mass balance equations -- Non-equation-based models -- Experimental determination of specific rates -- Optimization via Pontryagin's maximum principle -- Computational techniques -- Optimization of single and multiple isothermal reactions -- Optimization of fed-batch cultures for cell mass production -- Optimization of fed-batch cultures for metabolites -- Simple, intuitive adaptive optimization -- Measurements, estimation and control -- Feasibility assessment and implementable feed rates. | |
520 | |a Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal and sub-optimal fed-batch operations. Numerous examples are provided to illustrate the application of optimal fed-batch cultures. This unique book, by world experts with decades of research and industrial experience, is a must for researchers and industrial practitioners of fed-batch processes (modeling, control and optimization) in biotechnology, fermentation, food, pharmaceuticals and waste treatment industries. | ||
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