The effect of sex hormones on anterior tibial displacement and anterior tibial shear in normal ovulating women and oral contraceptive users.

The purpose of this study was to determine the effect of fluctuating hormone levels on anterior tibial displacement (ATD) and anterior tibial shear (ATS) both in ovulating women and in oral contraceptive users. Eighteen uninjured, ovulating women (NORM) and 20 oral contraceptive (OC) users participa...

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Bibliographic Details
Main Author: Verscheure, Susan D.
Format: Thesis Electronic eBook
Language:English
Published: 2003
Subjects:
Online Access:Static URL is not available. In OregonPDF, search for the Author using the All tab.
Static URL is not available. In OregonPDF, search for the Author using the All tab

MARC

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245 1 4 |a The effect of sex hormones on anterior tibial displacement and anterior tibial shear in normal ovulating women and oral contraceptive users. 
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520 |a The purpose of this study was to determine the effect of fluctuating hormone levels on anterior tibial displacement (ATD) and anterior tibial shear (ATS) both in ovulating women and in oral contraceptive users. Eighteen uninjured, ovulating women (NORM) and 20 oral contraceptive (OC) users participated. The NORM subjects were tested for ATD, ATS, and hormones at three time periods during one complete menstrual cycle, including: 1) the immediate onset of menses (M1), 2) the estimated occurrence of estrogen peak (E), and 3) the immediate onset of the next menses (M2). OC subjects were tested after ingesting estrogen supplements for 7 days (E), and when no supplement was taken (M1, M2). ATD was produced by instrumented forces (KT-2000) and ATS was recorded on a closed-chain dynamometer. Hormone levels were assessed for each test time in the NORM group. ANOVA were used to identify significant differences in ATD and ATS (P<0.05), if any, between test periods, groups, and conditions. No significant differences in ATD or ATS were found; however, the effect of test time on normalized ATD approached significance (P<0.08). The predominant pattern of ATD and ATS change across time period in the NORM group (7 of 18 subjects) was an increase from M1 to E and a decrease from E to M2. The predominant pattern of ATD (6 of 20 subjects) and ATS (9 of 20 subjects) change across test time observed for the OC group was a decrease from M2 to E and an increase from E to M2, the opposite of the NORM group. There were no significant correlations between hormone levels and ATD or ATS across all NORM subjects, but significant correlations (P<0.05) were observed in this sub-group with the predominant pattern (7 of 18 subjects). Peak blood estrogen levels occurring during ovulation may be linked to an increase in ATD and ATS in some ovulating women, and ingested synthetic hormones may be linked to a decrease in ATD and ATS in some OC users. Changes in ATD may be due to a temporary effect of estrogen or synthetic progestin on ACL tissue, and changes in ATS may be due to a transient effect of natural or synthetic hormones on quadriceps activation. 
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