Design and optimization in organic synthesis /
Revised, and updated Design and Optimization in Organic Synthesis presents strategies to explore experimental conditions and methodologies for systematic studies of entire reaction systems (substrates, reagent(s), catalyst(s), and solvents). Chemical phenomena are not usually the result of a single...
Saved in:
Main Author: | |
---|---|
Other Authors: | |
Format: | Electronic eBook |
Language: | English |
Published: |
Amsterdam ; San Diego, CA :
Elsevier,
2005.
|
Edition: | 2nd rev. and enl. ed. |
Series: | Data handling in science and technology ;
v. 24. |
Subjects: | |
Online Access: | CONNECT |
MARC
LEADER | 00000cam a2200000 a 4500 | ||
---|---|---|---|
001 | in00006552579 | ||
006 | m o d | ||
007 | cr cn||||||||| | ||
008 | 070806s2005 ne a ob 001 0 eng d | ||
005 | 20240708134629.8 | ||
010 | |z 2006355502 | ||
035 | |a 1WRLDSHRocn162579979 | ||
040 | |a OPELS |b eng |e pn |c OPELS |d OKU |d OPELS |d OCLCQ |d N$T |d YDXCP |d EBLCP |d MERUC |d E7B |d IDEBK |d DEBBG |d OCLCQ |d OCLCO |d DEBSZ |d OCLCQ |d OCLCF |d OCLCQ |d STF |d D6H |d OCLCQ |d LEAUB |d OL$ |d OCLCQ |d OCLCO |d OCLCQ |d INARC |d OCLCO | ||
019 | |a 122942899 |a 441764173 |a 647546692 |a 1035662093 |a 1357631452 | ||
020 | |a 9780444515278 | ||
020 | |a 0444515275 | ||
020 | |a 9780080455273 |q (electronic bk.) | ||
020 | |a 0080455271 |q (electronic bk.) | ||
020 | |z 0444518851 |q (CD-ROM) | ||
024 | 3 | |z 9780444515278 | |
035 | |a (OCoLC)162579979 |z (OCoLC)122942899 |z (OCoLC)441764173 |z (OCoLC)647546692 |z (OCoLC)1035662093 |z (OCoLC)1357631452 | ||
037 | |a 102789:102808 |b Elsevier Science & Technology |n http://www.sciencedirect.com | ||
050 | 4 | |a QD262 |b .C32 2005eb | |
070 | |a QD262 |b .C32 2005 | ||
082 | 0 | 4 | |a 547.2 |b C197d2005 |2 22 |
049 | |a TXMM | ||
100 | 1 | |a Carlson, Rolf, |d 1946- | |
245 | 1 | 0 | |a Design and optimization in organic synthesis / |c Rolf Carlson, Johan E. Carlson. |
250 | |a 2nd rev. and enl. ed. | ||
260 | |a Amsterdam ; |a San Diego, CA : |b Elsevier, |c 2005. | ||
300 | |a 1 online resource (xx, 574 pages) : |b illustrations | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
490 | 1 | |a Data handling in science and technology, |x 0922-3487 ; |v v. 24 | |
504 | |a Includes bibliographical references and index. | ||
505 | 0 | |a Strategies on different levels in organic synthesis -- Experimental study of reaction conditions : initial remarks -- Models as tools -- General outline of screening experiments -- Two-level factorial designs -- Two-level fractional factorial designs -- Other designs for screening experiments -- Summary of screening experiments -- Optimisation -- Steepest ascent -- Simplex methods -- Response surface methods -- Reaction kinetics by sequential response surface modelling -- Summary of strategies for exploring the experimental space -- The reaction space -- Principal properties -- Strategies for the selection of test systems -- Quantitative relations : observed responses and experimental variations -- Exploring discrete variations : near-orthogonal experiments by singular value decomposition -- Optimization when there are several responses variables -- A method for determining suitable order of introducing reagents in "one-pot" procedures. | |
520 | |a Revised, and updated Design and Optimization in Organic Synthesis presents strategies to explore experimental conditions and methodologies for systematic studies of entire reaction systems (substrates, reagent(s), catalyst(s), and solvents). Chemical phenomena are not usually the result of a single factor and this book describes how statistically designed methods can be used to analyse and evaluate synthetic procedures. The methodology is based on multivariate statistical techniques. The accompanying CD contains data tables and programmes. This book is essential reading for anyone working in process design and development in fine chemicals or the pharmaceutical industry, and is suitable for those with no experience in the field. * Contains recalculated models and redrawn figures, as well as new chapters on for example, the design of combinatorial libraries * Presents strategies to explore experimental conditions and methodologies * Enables the analysis and prediction of the best synthetic procedures. | ||
588 | 0 | |a Print version record. | |
500 | |a ScienceDirect eBook - Chemistry pre-2007 (Elsevier and Woodhead) |5 TMurS | ||
650 | 0 | |a Organic compounds |x Synthesis. | |
655 | 0 | |a CD-ROMs. | |
700 | 1 | |a Carlson, Johan E., |d 1973- | |
730 | 0 | |a WORLDSHARE SUB RECORDS | |
776 | 0 | 8 | |i Print version: |a Carlson, Rolf, 1946- |t Design and optimization in organic synthesis. |b 2nd rev. and enl. ed. |d Amsterdam ; San Diego, CA : Elsevier, 2005 |z 0444515275 |z 9780444515278 |w (OCoLC)59080831 |
830 | 0 | |a Data handling in science and technology ; |v v. 24. |x 0922-3487 | |
856 | 4 | 0 | |u https://ezproxy.mtsu.edu/login?url=https://www.sciencedirect.com/science/bookseries/09223487/24 |z CONNECT |3 Elsevier |t 0 |
949 | |a ho0 | ||
994 | |a 92 |b TXM | ||
998 | |a wi |d z | ||
999 | f | f | |s bfc13514-5451-46c2-8469-dd236a9ddae3 |i 0335bef6-dbd0-4276-a0a9-38a5cbd7fbdd |t 0 |
952 | f | f | |a Middle Tennessee State University |b Main |c James E. Walker Library |d Electronic Resources |t 0 |e QD262 .C32 2005eb |h Library of Congress classification |