Drug and therapy development for triple negative breast cancer /

In Drug and Therapy Development for Triple Negative Breast Cancer, a team of distinguished practitioners delivers an in-depth and authoritative discussion of contemporary methods for treating triple negative breast cancer (TNBC). The editors have included material that covers its molecular causes, i...

Full description

Saved in:
Bibliographic Details
Other Authors: Kendrekar, Pravin (Editor), Adimule, Vinayak (Editor), Hurst, Tara (Editor)
Format: Electronic eBook
Language:English
Published: Weinheim, Germany : Wiley-VCH, [2023]
Subjects:
Online Access:CONNECT
Table of Contents:
  • Intro
  • Title Page
  • Contents
  • Preface
  • Part I History of Breast Cancer
  • 1 Early-Stage Diagnosis of Breast Cancer: Amelioration in Approaches
  • 1.1 Introduction
  • 1.2 Imaging Techniques
  • 1.2.1 Mammography (MG)
  • 1.2.2 Ultrasonography (US)
  • 1.2.3 Magnetic Resonance Imaging (MRI)
  • 1.3 Microwave Breast Imaging Methods
  • 1.3.1 Microwave Tomography
  • 1.3.2 Radio-Based Microwave Imaging
  • 1.4 Biomarkers and Biosensors for Breast Cancer Detection
  • 1.4.1 Biomarkers
  • 1.4.2 Biosensors
  • 1.5 Conclusion
  • Acknowledgment
  • Conflict of Interest
  • Authors Contribution
  • 2.4.2 Chromosome Segregation Defect Check by HR Repair
  • 2.4.3 Aging, Cell Death, and Senescence
  • 2.5 Therapeutic Approach
  • 2.6 Conclusion
  • Abbreviations
  • References
  • 3 Recent Advancement of Nanotherapeutics to Treat Breast Cancer
  • 3.1 Introduction
  • 3.2 Pathophysiology of Breast Cancer
  • 3.3 Classification of Breast Cancer
  • 3.4 Techniques for Breast Cancer Detection
  • 3.5 Current Breast Cancer Therapies
  • 3.6 Nanotherapeutics for Breast Cancer Treatment and Metastasis
  • 3.6.1 Nanodiamonds (NDs)
  • 3.6.2 Intrinsic Toxicity Reduction
  • 3.6.3 Diminishing Chemoresistance (CR)
  • 3.6.4 Delivery of Combination Therapeutics Through NDs
  • 3.7 Polymer-Based Nanoparticles (PBNPs)
  • 3.8 Inorganic Nanoparticles (IONPs)
  • 3.9 Hydrogels (HGLs) and Microbubbles (MBs)
  • 3.10 Recent Patents of Nanotherapeutics for Breast Cancer Treatment
  • 3.11 Clinical Trials of Nanotherapeutics for Breast Cancer
  • 3.12 Conclusion and Future Perspectives
  • References
  • 4 HER Receptor in Breast Cancer
  • 4.1 Introduction
  • 4.2 Role of HER Receptors in the Human Body
  • 4.3 HER2 Receptor in Breast Cancer Progression
  • 4.4 Conclusion
  • Conflict of Interest
  • References
  • 5 Human Endogenous Retroviruses in Triple-Negative Breast Cancer
  • 5.1 Introduction
  • 5.2 HERVs in Breast Cancer and TNBC
  • 5.3 TROJAN lncRNA and TNBC
  • 5.4 HERVs and Breast Cancer Treatments
  • 5.5 Conclusion
  • 5.6 Search Strategy
  • References
  • Part II Novel Drug Discovery and Development
  • 6 Development in Drug Repurposing for the Treatment of Acute Leukemia Complicating Metastatic Breast Cancer
  • 6.1 Introduction
  • 6.1.1 Acute Leukemia's
  • 6.1.2 Mitochondrial cAMP-PKA Signaling
  • 6.1.3 Nuclear Compartment
  • 6.1.4 Cytosolic Compartment and Plasma Membrane
  • 6.2 Conclusion