Cell culture engineering : recombinant protein production /
Offers a comprehensive overview of cell culture engineering, providing insight into cell engineering, systems biology approaches and processing technology In Cell Culture Engineering: Recombinant Protein Production, editors Gyun Min Lee and Helene Faustrup Kildegaard assemble top class authors to pr...
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Other Authors: | , |
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Format: | eBook |
Language: | English |
Published: |
Weinheim, Germany :
Wiley-VCH,
[2020]
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Series: | Advanced biotechnology ;
v. 9. |
Subjects: | |
Online Access: | CONNECT CONNECT |
Table of Contents:
- 1. Platform Technology for Therapeutic Protein Production
- 2. Cell Line Development for Therapeutic Protein Production
- 3. Transient Gene Expression-Based Protein Production in Recombinant Mammalian Cells
- 4. Enhancing Product and Bioprocess Attributes Using Genome-Scale Models of CHO Metabolism
- 5. Genome Variation, the Epigenome and Cellular Phenotypes
- 6. Adaption of Generic Metabolic Models to Specific Cell Lines for Improved Modeling of Biopharmaceutical Production and Prediction of Processes
- 7. Toward Integrated Multi-omics Analysis for Improving CHO Cell Bioprocessing
- 8. CRISPR Toolbox for Mammalian Cell Engineering
- 9. CHO Cell Engineering for Improved Process Performance and Product Quality
- 10. Metabolite Profiling of Mammalian Cells
- 11. Current Considerations and Future Advances in Chemically Defined Medium Development for the Production of Protein Therapeutics in CHO Cells
- 12. Host Cell Proteins During Biomanufacturing
- 13. Mammalian Fed-batch Cell Culture for Biopharmaceuticals
- 14. Continuous Biomanufacturing
- 15. Process Analytical Technology and Quality by Design for Animal Cell Culture
- 16. Development and Qualification of a Cell Culture Scale-Down Mode
- References
- Index.