Antibiotics : actions, origins, resistance /
A comprehensive account of the structural classes of antibiotics that have impacted human infectious disease. " Provides an introduction to antibiotics and examines how antibiotics block specific proteins acting in essential bacterial processes and how the molecular structure of the small-molec...
Saved in:
| Main Author: | |
|---|---|
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Washington, D.C. :
ASM Press,
©2003.
|
| Subjects: | |
| Online Access: | CONNECT |
Table of Contents:
- Antibiotics : initial concepts
- Introduction to major antibiotic classes and modes of action
- Antibiotics that act on cell wall biosynthesis
- Antibiotics that block bacterial protein biosynthesis
- Antibiotics that block DNA replication and repair : the Quinolones
- Other targets of antibacterial drugs
- Natural and producer immunity versus acquired resistance
- Enzymatic destruction or modification of the antibiotic by resistant bacteria
- Antibiotic resistance by efflux pumps
- Antibiotic resistance by replacement or modification of the antibiotic target
- Regulation of antibiotic biosynthesis in producer organisms
- Polyketide antibiotic biosynthesis : assembly line enzymology
- Enzymatic assembly lines for nonribosomal peptide antibiotics
- Biosynthesis of other classes of antibiotics
- New looks at targets
- New molecules
- Contexts and challenges for the use of new antibiotics.
