MicroRNAs in medicine /

"MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions...

Full description

Saved in:
Bibliographic Details
Other Authors: Lawrie, Charles H. (Editor)
Format: eBook
Published: Hoboken, New Jersey : Wiley-Blackwell, [2013]
Online Access:CONNECT
Table of Contents:
  • Title page; Copyright page; Foreword; Preface; Contributors; 1: MicroRNAs: A Brief Introduction; I. A Short History of Small RNAs; II. Biogenesis of miRNAs; III. miRNA Function: Controlling mRNA Stability, Degradation, and/or Translation; IV. Regulating the Regulators: miRNA Control and Dysfunction in Disease; V. Present and Future Perspectives for miRNAs in Medicine; PART I: MicroRNAs as Physiological Regulators; 2: MicroRNA Regulation of Stem Cell Fate and Reprogramming; I. Introduction
  • II. MicroRNAs in Pluripotency and Establishment of Different LineagesIII. MicroRNAs, Induced Pluripotency, and Transdifferentiation; IV. Conclusion; Acknowledgments; 3: MicroRNAs as Regulators of Immunity; I. Introduction; II. Innate Immunity and miRNAs; III. Adaptive Immunity and miRNAs; IV. Conclusions and Future Directions; 4: Regulation of Senescence by MicroRNAs; I. Introduction: Senescence; II. Posttranscriptional Regulation of Senescence by miRNAs; III. Impact of SA-miRNAs on In Vivo Senescence
  • IV. Concluding Remarks and Future PerspectivesAcknowledgments; 5: The Emergence of GeroMIRs: A Group of MicroRNAs Implicated in Aging; I. Introduction; II. MiRNAs and Aging: Lessons from Invertebrates; III. Changes in miRNA Expression during Mammalian Aging; IV. MiRNA Modulation of Mammalian DNA Damage; V. Micromanaging of Other Aging-Associated Pathways in Mammals; VI. Conclusions and Future Perspectives; 6: MicroRNAs and Hematopoiesis; I. Introduction; II. Lymphocyte Development; III. Monocyte and Granulocyte Development
  • IV. Erythrocyte and Megakaryocyte DevelopmentV. Conclusions; 7: MicroRNAs in Platelet Production and Activation; I. Introduction; II. miRNA Biogenesis and Function; III. miRNAs and Megakaryocytopoiesis; IV. Platelet miRNAs; V. Platelet miRNAs as Biomarkers; VI. Platelet Microparticles and miRNAs; VII. Summary and Future Directions; PART II: MicroRNAs in Infectious Disease: Hostâ€Pathogen Interactions; 8: MicroRNAs as Key Players in Host-Virus Interactions; I. Introduction; II. Host miRNAs and Virus Infection; III. Viral miRNAs
  • IV. Biological Roles of Viral miRNAsV. Conclusions and Future Prospects; Acknowledgments; 9: MicroRNA Expression in Avian Herpesviruses; I. Introduction; II. Avian Herpesviruses and Associated Diseases; III. Identification of miRNAs Encoded by Avian HerpesvirusES; IV. Viral Orthologues of Host miRNAs; V. Target Identification of Avian Herpesvirus miRNAs; VI. Conclusions; Acknowledgment; 10: Function of Human Cytomegalovirus MicroRNAs and Potential Roles in Latency; I. Introduction to Human Cytomegalovirus